Gradient Dissent: Conversations on AI

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All Episodes

He Raised $70M to Cure Every Disease With AI | Samuel G. Rodriques, Edison Scientific

Samuel Rodriques left physics because there were no unsolved problems left.Instead, he built an AI scientist named Kosmos to cure every disease, solve aging, and map the human brain.In this episode:The cure his AI proposed for blindnessWhy he would never touch a peptideWhether we ... Show more

. 1h 14min

Uber, Nissan, and Mercedes Chose This Self-Driving Startup | Alex Kendall, Wayve

"Every vehicle is capable of driverless operation. That's clearly the steady state of where we're going."Wayve started in a rented house in Cambridge with $1.5M, a car in the garage, and an aim to integrate end-to-end AI into driving. A decade later it's driven across 506 cities ... Show more

. 45min 49sec

Why Netflix, Uber, and Spotify Never Lag: The Database Nobody Talks About | Aaron Katz

"Companies designing for agents, not humans, are going to get a lot of lift."ClickHouse started as an internal tool at Yandex. Today it's the database Anthropic, OpenAI, Meta and Tesla all run on.In this episode, CEO Aaron Katz joins Lukas Biewald to talk about how he turned an o ... Show more

. 43min 31sec

The $64M Bet on an AI That Has to Be Right | Carina Hong, CEO of Axiom

Formal verification already consumes years of human effort.In this episode, Lukas Biewald talks with Carina Hong, Founder & CEO of Axiom, about why verification is becoming the real bottleneck in high stakes AI systems.They discuss how Axiom uses AI to take on the tedious checkin ... Show more

. 50min 40sec

What a $42B Software Co. Really Spends on AI Tools

“I don't worry about being replaced by AI. I worry about being replaced by someone who's really good at using AI.”Atlassian has 10,000+ engineers currently split-testing the world’s top AI coding tools, from GitHub Copilot and Cursor to Claude Code. In this episode, Co-Founder & ... Show more

. 1h 7min