TWiP 97: The seven year itch

TWiP solves the case of the 3 yo child, who recently immigrated to the US from Central America, in the ER with acute right lower quadrant abdominal pain and a rather active serpiginous wormlike 'thing' wiggling away in the child's appendix. Hosts: Vincent Racaniello, Daniel Griff ...  Show more

TWiP reviews a phase 2 clinical trial of a recombinant vaccine against N. americanus glutathione S-transferase-1, an enzyme that performs a crucial enzymatic step in hookworm blood feeding. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Pod ...  Show more

Daniel Griffin discusses a front-line health care worker survey, pre-exposure seropositivity and subsequent infection in healthy young adults, fitted filtration efficiency of double masking, BinaxNow rapid in-home antigen test, postvaccination infections in a nursing facility, ...

Picture it: you’re on a crowded subway and someone sneezes. Or maybe you’re on a plane and the person next to you keeps coughing. Perhaps you shook hands with someone who didn’t wash their hands after going to the bathroom. Interaction with germs is inevitable, but why do some pe ...  Show more

Multiple sclerosis, lupus, rheumatoid arthritis, even psoriasis — these are diseases in which the body begins to attack itself, and they all have one thing in common: they affect women more than men. Most autoimmune disorders do. And not just by a little bit, often by a lot; i ...

Last summer, at a hospital in England, a man in his 70s being treated for complications with cancer tested positive for covid-19. He had lymphoma, and the disease plus his drugs weakened his immune system, making him particularly susceptible to the virus. He wasn’t too bad off ...