14. Why Do Most Ideas Fail to Scale?

14. Why Do Most Ideas Fail to Scale?

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32. Why Has There Been So Little Progress on Alzheimer’s Disease?

One possibility: a leading hypothesis pursued by researchers (and funders) was built on science that now appears to be fraudulent. Stephen Dubner speaks with the scientist and the journalist who blew the whistle. SOURCES: Charles Piller, investigative journalist for Science, auth ...  Show more

The Most Powerful People You’ve Never Heard Of (Update)

Just beneath the surface of the global economy, there is a hidden layer of dealmakers for whom war, chaos, and sanctions can be a great business opportunity. In this updated episode from 2025, journalists Javier Blas and Jack Farchy help us shine a light on the shadowy realm of c ...  Show more

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In a new book called The Voltage Effect, the economist John List — who has already revolutionized how his profession does research — is trying to start a scaling revolution. In this installment of the Freakonomics Radio Book Club, List teaches us how to avoid false posi ...

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In his new book, “Rationality: What It Is, Why It Seems Scarce, Why It Matters,” Steven Pinker writes: “When humans set themselves the goal of improving the welfare of their fellows … and they apply their ingenuity in institutions that pool it with others’, they occasionally succ ...  Show more