Podcast 797: Vitamin C in Sepsis

Contributor; Aaron Lessen, MD Educational Pearls: A 2026 survey asked Canadian emergency medicine (EM) physicians about their eating and drinking habits while on shift. Among 527 respondents, 35% reported that they never or hardly ever ate during shifts, and 37% said the same abo ...  Show more

Contributor; Taylor Lynch, MD Educational Pearls: Thoracotomy Thoracotomy is used in traumatic cardiac arrest to replace conventional CPR with direct access to the chest. Goals include identifying and controlling reversible causes of bleeding, prioritizing blood flow to the heart ...  Show more

<span class="s1">In this episode, we discuss the role of hydrocortisone, ascorbic acid (Vitamin C) and thiamine (HAT therapy) in the treatment of patients with septic shock. We discuss biological plausibility and comprehensively review the latest evidence.</span>

Every day, approximately 30,000 people die globally of sepsis. The condition comes about when your immune system overreacts to an infection, leading potentially to organ failure and death. There is no cure. But then in 2017, a doctor proposed a novel treatment for sepsis, a mixtu ...  Show more

IV Thiamine may be helpful to improve the outcomes of critically ill (ICU) patients who have sepsis or septic shock. Show Notes: https://eddyjoemd.com/iv-thiamine TrueLearn Link: ⁠ https://truelearn.referralrock.com/l/EDDYJOEMD25/⁠ Discount code: EDDYJOEMD25 Although great care ha ...  Show more

In this episode, we delve into the groundbreaking study "Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction." We explore how Therapeutic Plasma Exchange (TPE) could revolutionize the tr ...  Show more