Is Depression a Chemical Imbalance?

In this episode, Dr. David Puder and the Tuesday 2025–2026 Psychotherapy Cohort explore mature and neurotic defense mechanisms through the lens of Nancy McWilliams' influential framework. Building upon the previous discussion on primitive defenses, they provide an in-depth look a ...  Show more

In this episode, Dr. David Puder and his talented Cohort deliver a comprehensive exploration of primitive defense mechanisms, which are the earliest, most fundamental ways the mind protects us from overwhelming anxiety, trauma, and threats to the self. Drawing directly from Nancy ...  Show more

For more ways to manage depression check out my course, Change Your Brain: 10 Natural, Research-Backed Ways to Improve Mental Health https://courses.therapyinanutshell.com/change-your-brain

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This episode, I explain what major depression is at the biological and psychological level and the various treatments that peer-reviewed studies have revealed can help prevent and treat depression. I explain the three major chemical systems that are altered in depression: norepin ...  Show more

Nearly one in five US adults are diagnosed with depression at some point in their lives. As the use of antidepressants have steadily risen since their introduction in the 1980s, what have we learned about depression? Is depression truly a “chemical imbalance” of the brain? And wh ...  Show more

Monoaminmangelhypothese: Studienlage und alternative Erklärungsmodelle