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Also known as "The Derby Poisoner," Lydia Sherman poisoned, in total, her three husbands plus as many as eight children in her care --- six of whom were her biological children. She confessed to her murders, showing no remorse, was convicted of second-degree murder in 1872.

Italian noblewoman Lucrezia Borgia was the illegitimate daughter of Cardinal Rodrigo Borgia, who would later become Pope Alexander VI. Considered a famous beauty during the Italian Renaissance, she also notoriously rivaled her family members in jealousy, intrigue, and homicide ...

There's more than one suspicious person in this case, and it's time to explore them all. Plus a twist that could be a big break or another white rabbit. 

A story about religion, sex, an assassination, and silverware. Say hello on Twitter, Facebook and Instagram. Sign up for our occasional newsletter, The Accomplice. Follow the show and review us on Apple Podcasts: iTunes.com/CriminalShow. Sign up for Criminal Plus to get behind-th ...  Show more

One of the world's most prolific serial killers... basically lives up to the hype. The only thing we can clear her of is her gruesome bathing practices! Learn more about your ad choices. Visit megaphone.fm/adchoices 

Women love true crime. But who is profiting off of it and what about the people directly impacted? 

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