Episode 380: Dopamine Misconceptions

In this episode, I'm honored to welcome Dr. Tracy Hicks, a dual-certified family and mental health nurse practitioner with over two decades of clinical experience—and a deeply personal connection to serious mental illness. Dr. Hicks is both the daughter of a parent and the mother ...  Show more

In this episode, I share the absolute honest truth about my life at the moment. I also talk about my focus for this year, the phrases I can't get out of my head, and the things I'm grateful for from the last year. Let's do this. Got a question for the show? Email duffthepsych@gma ...  Show more

If you have severe depression, PTSD, or anxiety that just won’t go away despite therapy and medication you should know about Ketamine. 30-40% of people with depression have treatment-resistant depression (that means that you’ve tried at least 2 types of medication and it isn't ...

In this episode, I explain how ketamine causes rewiring of brain circuits and dissociative states to relieve symptoms of depression and post-traumatic stress disorder (PTSD). I explain how ketamine impacts both the brain’s glutamate and its endogenous opioid pathways, which toget ...  Show more

This episode, I explain what major depression is at the biological and psychological level and the various treatments that peer-reviewed studies have revealed can help prevent and treat depression. I explain the three major chemical systems that are altered in depression: norepin ...  Show more

This episode serves as a sort of “Dopamine Masterclass”. I discuss the immensely powerful chemical that we all make in our brain and body: dopamine. I describe what it does and the neural circuits involved. I explain dopamine peaks and baselines, and the cell biology of dopamine ...  Show more