At Home with Neil Patrick Harris, His Fiancé ...

In every life, there are defining moments when a person must decide whether to stand up for what is right or remain silent. At a young age, Pakistani activist Malala Yousafzai began boldly advocating for girls' access to education, which had been denied by the Taliban, an extremi ...  Show more

Oprah sits down with Carole Bayer Sager, the Grammy-, Golden Globe- and Oscar-winning singer/songwriter and painter, to discuss her legendary career. Carole shares the stories behind some of her biggest songs, including "That's What Friends Are For" and "The Prayer." One of the m ...  Show more

Original Airdate: April 21, 2009

Over the years, Oprah has interviewed close to 28,000 people from all walks of life. Let’s take a look back on the interviews we'll never forget. We’ll revisit the Mississippi man who shed over 300 pounds, the ex-husband of Susan Smith, t ...

Original Air Date: 10/02/2009

Everyone thought they were crazy. This family had not one, not two, but 44 kids! Plus, the little family who's living large, once conjoined twins and the history-making sextuplets.

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Original Air Date: January 25, 2011

Oprah takes a look back at 25 years of gay topics. She updates several guest’s stories and talks about how perceptions of LGBQT+ people have changed over the years. Olympic gold medal winner Greg Louganis talks about his landmark decis ...

Original Airdate: April 15, 2009

Computers, mobile phones and social networks are just some of the tools that these sexual predators have at their fingertips. Oprah talks with the families of children who were preyed upon online, sharing their stories with the hope that ...