TWiPO #110: Discussing the ”Gift from a Child...

In this episode Dr. Timothy Cripe and Dr. Brenda Weigel are joined by FDA's Dr. Nicole Drezner, pediatric oncologist and the Deputy Division Director of the Division of Oncology 2 who led the FDA review and publication on the approval of DFMO. Listen in on the discussion surround ...  Show more

Dr. Luca Szalontay,  Assistant Professor of Pediatrics at Columbia University Medical Center, discusses the work of Columbia's Initiative for Drug Delivery Innovation which is exploring new treatments for pediatric brain tumors utilizing Convection Enhanced Delivery and Focused U ...  Show more

Dr. Sanjay Gupta sits down with Dr. Marty Makary, U.S. FDA Commissioner to dig beyond the headlines of this Administration’s latest efforts to “Make America Healthy Again.” This conversation took place on Friday, September 26th, 2025. Our show was produced by Jennifer Lai, with a ...  Show more

I was invited to participate in the FDA roundtable on menopausal hormone therapy. I declined. In this episode, I’m going to tell you why. A brief history of the FDA Why there is a black box warning on all estrogen products Why the black box warning should be removed from all loca ...  Show more

Human epidermal growth factor receptor 2 (HER2) is overexpressed in multiple cancers, including breast, gastric, colorectal, and epithelial ovarian cancers. However, this receptor's complexity doesn't stop there. It has multiple subdomains and various responses to drugs, and t ...

Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from <a class="related-article" href= "https://jamanetwork.com/journals/jama/f ...