The Effect of Histone Demethylases on Gene Ex...

In this episode we speak with Luke Isbell, Senior Research Fellow and group leader at Adelaide University and the South Australian immunoGENomics Cancer Institute. We discuss his work on transcription factors, chromatin, and how epigenetic marks on histones can influence transcri ...  Show more

In this episode we speak with Rob Klose, Professor of Genetics at the University of Oxford, about how CpG islands help control gene expression and chromatin regulation during development. We discuss how his lab connected CpG islands to histone modifications and chromatin regulati ...  Show more

On today’s episode we are discussing the results and implications of a recent study that describes the creation of a new set of tools to turn off or on any region in the genome with high specificity. Host Lauren Richardson and a16z general partner Vijay Pande are joined by the ...

Transcription is a tightly regulated process, where chemical modifications initiate the duplication of genetic material. This epigenetic process is often dysregulated in cancer, but it can be targeted with small molecule inhibitors. EPIGENETIC SIGNALLING Professor Panagis Filippa ...  Show more

In this episode of Blood Cancer Talks, hosts Eddie, Ashwin, and Raj welcome two distinguished experts to explore the cutting-edge field of circulating tumor DNA (ctDNA) in B-cell lymphomas. Dr. David Russler-Germain, a lymphoma clinician from Siteman Cancer Centre at Washington U ...  Show more

References

Cell Death & Differentiation 2020.27: 3374–3385 

Cell Death & Differentiation 2019. 26: 1501–1515

Cancers  2020, 12(8), 2137.