Neuroepigenetic Mechanisms and Primate Epigen...

In this episode of the Epigenetics Podcast, we talked with Will Wang from Sanford Burnham Prebys about his work on muscle stem cell repair, regeneration, and aging, exploring spatial-omics and machine learning. We begin our conversation by exploring the traditional concepts of sp ...  Show more

In this episode of the Epigenetics Podcast, we talked with Mitch Guttman from Caltec about ChIP-DIP (ChIP-Done In Parallel). ChIP-DIP is a newly developed approach for high-resolution protein–DNA interaction mapping. The method uses antibody-guided isolation of denaturant-insolub ...  Show more

This week, Patrick welcomes President and CEO of The Jackson Laboratory, Lon Cardon. They discuss the rise of genome-wide association studies (GWAS) and how they changed the face of genetics research and why Lon took the plunge and moved from academia to industry in an era when i ...  Show more

In this episode, we explore key topics in genetics, including how sex-linked and autosomal traits are inherited. We'll break down inheritance patterns using real-world examples, like X-linked recessive diseases, and walk through Punnett square problems to show how these traits ar ...  Show more

Jacob Kimmel thinks he can find the transcription factors to reverse aging. We do a deep dive on why this might be plausible and why evolution hasn’t optimized for longevity. We also talk about why drug discovery has been getting exponentially harder, and what a new platform for ...  Show more

Kristen Hawkes' "Grandmother Hypothesis" provides a fascinating perspective on human evolution, menopause, and the unique social structures of humans. This theory posits that the long post-reproductive lifespan of women evolved because grandmothers played a critical ...