Episode 953: Penicillin Allergies

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Penicillin is the go-to antibiotic for many common infections - but in the UK more than 1-in-15 adults have a penicillin allergy label on their medical record. New research suggests that many with these labels are not actually allergic. Professor Sue Pavitt explains how more accu ...  Show more

Welcome to the party pal! The penicillin allergy assessment and delabelling party, that is. Callum takes Jame through the latest evidence base in antibiotic allergy in general, and beta lactam allergy assessment and management in particular. 

Links: 
PENFAST Score ...

We investigate the claim that an alternative antibiotic to cephalosporins (e.g., cefazolin) should be selected for penicillin-allergic patients in the perioperative setting. 

Claim 1. Alternative antibiotics may be as efficacious in preventing surgical site infections</ ...

A young woman with a history of penicillin allergy and an indication for penicillin treatment.  The discussion focuses on mechanisms of penicillin allergy and the utility of desensitization.

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