How to Succeed at Failing, Part 2: Life and D...

Economists don’t usually talk about “culture.” But Joel Mokyr argues that it’s the engine of innovation — and the Nobel Prize committee agreed. Stephen Dubner sits down for a thousand-year conversation (including advice!) with the new Nobel laureate. SOURCES: Joel Mokyr, economic ...  Show more

Just beneath the surface of the global economy, there is a hidden layer of dealmakers for whom war, chaos, and sanctions can be a great business opportunity. In this updated episode from 2025, journalists Javier Blas and Jack Farchy help us shine a light on the shadowy realm of c ...  Show more

Dr. James Lyons-Weiler is a scientist, researcher, CEO/President of IPAK-EDU, human rights advocate, host of Unbreaking Science, and author of CURES Vs. PROFITS: Successes In Translational Research, The Enviro ...

Also: are the most memorable stories less likely to be true? Stephen Dubner chats with Angela Duckworth in this classic episode from July 2020.

How can you learn to love uncertainty? Is it better to cultivate acceptance or strive for change? And, after 223 episodes, what is the meaning of life? 

As he finished his medical school exam, David Fajgenbaum felt off.  He walked down to the ER and checked himself in.  Soon he was in the ICU with multiple organ failure.  The only drug for his condition didn’t work. He had months to live, if that.  If he was going to survive, ...