639. “This Country Kicks My Ass All the Time”

It regulates 20 percent of the U.S. economy, and its commissioner has an aggressive agenda — faster drug approvals, healthier food, cures for diabetes and cancer. How much can he deliver? (Part two of “The Freakonomics Radio Guide to Getting Better.”) SOURCES:Marty Makary, commis ...  Show more

We all want to stay sharp, and forestall the cognitive effects of aging. But do brain supplements actually work? Are they safe? And why doesn’t the F.D.A. even know what’s in them? (Part one of “The Freakonomics Radio Guide to Getting Better.”) SOURCES:Marty Makary, commissioner ...  Show more

Popular podcasts in the "manosphere" helped sway young men to go MAGA in the 2024 election. New Yorker writer Andrew Marantz explains how Democrats can win them back. Also, Ken Tucker shares songs by Neil Young, Benjamin Booker and Teddy Swims. Learn more about sponsor message ch ...  Show more

Representative Marie Gluesenkamp Perez is one of just 13 Democrats to represent a district that Donald Trump won. Her distinctive economic message, and a willingness to buck her own party, helped her win re-election. But now the reality of the Trump era is coming home.

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The tariffs President Trump unveiled this week were both bigger than most people expected and a lot more confusing. These aren’t the flat tariffs he proposed during the campaign. And they aren’t reciprocal tariffs, as he claimed in his Rose Garden speech. So what is Trump actu ...

“It’s so insidious, people don’t realize it,” Barbara Kingsolver told me, describing the prejudice against “country people.” Kingsolver is one of those “country people,” as well as a literary legend in her own time, who set out to write the “great Appalachian novel.” And I thi ...