When Will AI Make Scientific Discoveries?

Anthropic dropped Claude Opus 4.6 and OpenAI responded with GPT 5.3 Codex just 20 minutes later — the most intense head-to-head model release we've ever seen. Here's what each model brings, how they compare, and what the first reactions are telling us. In the headlines: Google an ...  Show more

SaaS stocks are selling off hard as investors start pricing in AI agents as a direct threat to software’s growth, margins, and seat-based business models. This episode unpacks why markets suddenly believe something fundamental has shifted — and why claims of a full software apoca ...  Show more

What if AI could revolutionize healthcare with advanced language learning models? Sarah and Elad welcome Karan Singhal, Staff Software Engineer at Google Research, who specializes in medical AI and the development of MedPaLM2. On this episode, Karan emphasizes the importance of s ...  Show more

Scott and Daniel break down every month from now until the 2027 intelligence explosion.Scott Alexander is author of the highly influential blogs Slate Star Codex and Astral Codex Ten. Daniel Kokotajlo resigned from OpenAI in 2024, rejecting a non-disparagement clause and risking ...  Show more

Step inside DeepMind's laboratories and you'll find researchers studying DNA to understand the mysteries of life, seeking new ways to use nuclear energy, or putting AI to the test in mind-bending areas of maths. In this episode, Hannah meets Pushmeet Kohli, the head of science at ...  Show more

Our 126th episode with a summary and discussion of last week's big AI news!

NOTE: sorry about the poor audio quality :( will be better next week!

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