Interpretation of Clinical Trials That Stoppe...

Michelle A. Detry, PhD, Berry Consultants LLC, discusses The Intention-to-Treat Principle: How to Assess the True Effect of Choosing a Medical Treatment with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: The Intention-to-Treat Principle 

Roderick Little, PhD, University of Michigan School of Public Health Departments of Epidemiology & Biostatistics discusses Pattern-Mixture Models for Missing Data with Roger J. Lewis, MD, PhD, statistical editor for JAMA. Related Content: Pattern-Mixture Models for Missing Data 

Romina Brignardello-Petersen, DDS, PhD, and Gordon Guyatt, MD, of McMaster University talk with JAMA Executive Deputy Editor Robert Golub, MD, about how to interpret clinical practice guidelines and recommendations, the subject of a recent Users' Guides to the Medical Literatu ...

Tomas Kalincik, Head of the Clinical Outcomes Research Unit at the University of Melbourne, and Maria Pia Sormani, Professor of Biostatistics at the University of Genoa, discuss the use of real-world data to compare disease-modifying treatments (DMTs) in multiple sclerosis, inclu ...  Show more

JAMA Associate Editor Ethan Basch, MD, and Melanie Calvert, PhD, from the University of Birmingham, UK, discuss barriers to and strategies for including rigorous patient-reported outcomes in clinical trials, and reflect on Dr Calvert's recent JAMA paper on related ethical impl ...

One of the most common causes for problems we see in manuscripts at JAMA is an inappropriately calculated study sample size. This seemingly mysterious process is explained by Lynne Stokes, PhD, professor of Statistical Science at Southern Methodist University in Dallas, Texas.