TWiV 1356: Clinical update with Dr. Daniel Gr...

Paul Bieniasz joins TWiV to discuss his lab's discovery that the coronavirus nuclease NSP15 cuts viral RNA into oligonucleotides that are reinserted elsewhere in the viral RNA, generating insertion mutations at a frequency above 10⁻³ per genome, including new furin cleavage sites ...  Show more

TWiV reviews a landmark paper reporting the first generative design of complete viral genomes using AI, producing 16 viable bacteriophages that overcame antibiotic-resistant bacteria where natural phages could not, and a study suggesting that recombinant shingles vaccination redu ...  Show more

Hosts: Vincent Racaniello, Dickson Despommier, and Josef Sabo Vincent, Dickson, and Josef discuss tetraspanins on the surface of schistosomes as vaccine candidates and immune evasion proteins. Links for this episode: S. japonicum tetraspanin-2 as a vaccine target (PLoS NTP) Prote ...  Show more

Nels and Vincent review the identification of a novel virus associated with the pathogen Plasmodium knowlsei and which is part part of a diverse and unclassified viral taxon. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, RSS, email Become a patron of T ...  Show more

An adventuring Swedish doctor takes on a decades-long medical mystery: What exactly was the 1918 flu? This week, we’re sharing an episode of Science Vs, a podcast from Gimlet, a Spotify Studio. They talk to Dr. Johan Hultin, Eileen Hultin, Dr. Jeffery Taubenberger, Ann Reid, Rita ...  Show more

In this episode, we cover the topic of viruses. We explore a comprehensive range of subtopics including the definition and structure of viruses, their life cycles, and the differences between transduction and transfection. We also discuss virus classification, viral mutations, an ...  Show more