Lindsay Clancy Returns to Court as Prosecutor...

Two University of Mississippi students found dead in separate location, but both have kratom nearby. Kratom is a tropical evergreen tree, native to Southeast Asia. It's extract act as a psychoactive substanced. It's effects depending on the dose: at low doses it can act as a stim ...  Show more

A Texas man faces capital murder charges after a five-year-old girl was killed in a roadway shooting in Harris County. A Northern Virginia real estate agent was shot to death inside her home, triggering a multi-state manhunt that ended with her husband's arrest in Pennsylvania. O ...  Show more

A mystery in paradise unfolds when a British woman vanishes from her boyfriend’s luxury yacht in the U.S. Virgin Islands. Andrea Canning reports.

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A family vacation in Portugal turned into one of the most haunting disappearances in modern history. This is the story of Madeleine McCann — and the night she vanished from Apartment 5A. Learn more about your ad choices. Visit megaphone.fm/adchoices 

A young mother disappears. Investigators say her husband contacted spellcasters to put a hex on his wife so she wouldn’t leave him. "48 Hours" contributor Jonathan Vigliotti reports. 

When a beautiful young woman and her mother go missing, all eyes turn to the strange behavior of her father. And when he crumbles under the scrutiny, a lifetime of secrets make their way to the surface.