Remote Exercise SWEDEHEART: Cross-over Trial ...

The TRANQUILITY trial was designed to evaluate whether pacibekitug can reduce interleukin-6 (IL-6)-driven inflammation, a key inflammatory pathway increasingly linked to cardiovascular risk. Treatment with pacibekitug demonstrated favorable effects on inflammatory and cardiovascu ...  Show more

The CorCal Outcomes study showed that using coronary artery calcium (CAC) scoring to guide statin therapy for the primary prevention of atherosclerotic cardiovascular disease (ASCVD) was as effective as the Pooled Cohort Equations (PCE) in preventing major adverse cardiovascular ...  Show more

In patients with heart failure with low ejection fraction and chronic coronary disease without unstable symptoms, does stenting open blocked coronary arteries extend life or reduce hospitalizations? There is some literature to suggest those with low EF may benefit from revascular ...  Show more

In this episode, Dr. Harlan Krumholz introduces the September 16, 2025 issue of JACC, which features studies that challenge conventional clinical thinking, including a detailed ECMO physiology study showing that higher ECMO flow does not uniformly raise pulmonary capillary wedge ...  Show more

In this episode, Editor-in-Chief Harlan Krumholz explores the evolving landscape of cardiovascular medicine, beginning with a call for responsible stewardship of artificial intelligence. Highlights include a major registry study on percutaneous aspiration for right-sided endocard ...  Show more