A “living drug” that could change the way we ...

On paper, Blake Mycoskie is a glowing success story: he founded TOMS Shoes, building a global brand that has given away more than 100 million pairs of shoes to children in need. Yet despite his success, his struggle with depression nearly cost him his life. In this personal talk, ...  Show more

All children develop at different paces — so why do schools expect every student to learn the same way? Early education researcher Anna Rainio introduces "playworlds," a learning activity where adults and kids create imaginary stories together. She shows how pretend play helps st ...  Show more

Carl June, MD, an immunologist and oncologist at the University of Pennsylvania, joins Jorge Conde, general partner at a16z Bio + Health.

Together, Carl and Jorge talked about Carl's pioneering work in CAR T therapy — including the terrifying moment where he thought he h ...

In this episode of “Intention to Treat,” host Rachel Gotbaum explores the story of a teenager who’s now in remission from previously relapsed lymphoblastic leukemia and talks with the investigator who developed the “off-the-shelf” CAR T cells that made her treatment possible. A f ...  Show more

CAR T cells are genetically engineered to express a receptor that recognizes and kills tumor cells. CAR T-cell products are now FDA approved for 6 hematologic malignancies. Author Jennifer N. Brudno, MD, National Cancer Institute, joins JAMA Deputy Editor Mary McGrae McDermott ...

In this episode, Dr. Hind Rafei dives into the cutting-edge world of CAR-NK cell therapy and its potential to revolutionize cancer treatment. Unlike their T-cell counterparts, CAR-NK cells promise enhanced safety and innate tumor-killing ability. But what if their power could ...