Orphan Drugs

Neil MacGregor reflects on creating the landmark series that changed how people think about history. Then, revisit the Rosetta Stone, the artifact that unlocked ancient Egypt. Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week earl ...  Show more

In 1982, a twelve-year-old paperboy, Johnny Gosch, vanished from a quiet Iowa street and sparked an unlikely campaign: the faces of missing children printed on milk cartons by the billions. Roman Mars and Annie Brown trace how a regional dairy campaign exploded into a national sy ...  Show more

In the first of two episodes this week, we're taking a deep dive into the pharmaceutical industry. How much does the medication you take actually cost? What if a company came along and bought the rights to a particular drug and started charging double, triple, or even 10,000 time ...  Show more

When you get hurt, you go to a doctor. But what do you do when your doctor’s prescriptions turn you into an opioid addict? Johnny Simon and Tim Cronin tried one of the first legal battles in America to hold physicians accountable for over-prescribing opioids. And they won. Johnny ...  Show more

In the 1950s, Thalidomide was rolled out very quickly and what followed was a tragic story that highlighted perils of greed and hidden agendas. This week on Sawbones, Dr. Sydnee and Justin attempt to untangle this murky narrative, and highlight the doctor who heroically kept t ...

At the beginning of the 20th century, new medications were being discovered and created. The term ‘miracle drug’ was coined to describe the sudden positive effect of newly discovered remedies for once untreatable diseases and conditions. But, one person's cure can be ...