When the System Breaks Down, Leaders Stand Up

Ambition can open doors, but your principles determine where you go from there. In today’s episode, Ryan talks with entrepreneur and investor Codie Sanchez about how the four Stoic virtues of courage, discipline, justice, and wisdom can serve as a guide for building a successful ...  Show more

Heading into the weekend, here’s a reminder that not everything you do has to be useful, efficient, or productive. In this bonus episode, Ryan and Chris Guillebeau talk about making space for fun, following strange impulses, and doing the small things that make you feel more aliv ...  Show more

Three years into a global pandemic, the fact that infectious disease is capable of reshaping humanity is obvious. But seen in the context of sixty thousand years of human and scientific history, COVID-19 is simply the latest in a series of world-changing pathogens. In fact, the r ...  Show more

April 5, 1918. The first mention of a new influenza outbreak in Kansas appears in a public health report. That strain, later called the Spanish Flu, would go on to kill at least 50 million people worldwide. In a time before widespread global travel, how did this disease spread so ...  Show more

The way we die has been utterly transformed. There have been around 10,000 generations of human beings, but only in the last 3 or 4 have infectious diseases not been an expected and accepted cause of death. What drove the most deadly infectious diseases? Was technological progr ...  Show more

In October 1347, a ghostly fleet of trading ships docks at a port in Sicily. The crew members – dead already, or well on their way – bear bubonic plague. The ‘Great Pestilence’ will ravage the populations of three continents over the next decade. What changes to society will resu ...  Show more