The silence of the genes

Our antibiotics are failing us. In 2025, the UK Government said antibiotic resistance (AMR) contributes to more than 35,000 deaths each year in the UK. Emergency doctors say they are losing patients on a regular basis when they run out of ways to treat them. Antibiotics have save ...  Show more

Have you ever been told you aren't good enough to do something, then gone ahead and proved the naysayers wrong by doing it anyway - in glorious, headline-grabbing style? That is the satisfying story of Dr Dean Lomax. Dean grew up in Doncaster with a passion for fossils but after ...  Show more

The future is here. Gene silencing medicines - which can fine tune how our DNA works - have held promise for decades. Now hundreds of thousands of people will get them in the UK. James speaks to a surgeon whose life and career have been saved by gene-silencing drugs and to resear ...  Show more

There are plans to make high dose statins available over-the-counter without a prescription to improve uptake. Currently around two thirds of people likely to benefit most don't take them, but will these plans make a difference? Amyloidosis is a debilitating rare disease that is ...  Show more

Last week, a girl who was born deaf had her hearing restored following gene therapy. In the US, the first commercial gene therapy for sickle cell disease has just begun. And Great Ormond Street Hospital has found great success in their trials and a gene therapy for children lacki ...  Show more

ALS is a disease that destroys the nerve cells in the brain and spinal cord we need for voluntary movement. There is no cure, but now there is a newly approved medication that may slow down the disease and extend patients' lives. The drug, called Relyvrio, got its start with a co ...  Show more