Sample Size Calculation for a Hypothesis Test

Amyotrophic lateral sclerosis (ALS), which affects about 25 000 individuals in the US, causes progressive weakness but has varied presentations. Several FDA-approved medications are now available for ALS. Author John Ravits, MD, of UC San Diego School of Medicine joins JAMA Deput ...  Show more

Hepatitis B virus (HBV) infection affects around 254 million people worldwide and causes more than 1 million deaths annually. Author Anna Lok, MD, from the University of Michigan discusses HBV transmission, screening, and treatment with JAMA Associate Editor Beverly Forsyth, MD. ...  Show more

One of the most common causes for problems we see in manuscripts at JAMA is an inappropriately calculated study sample size. This seemingly mysterious process is explained by Lynne Stokes, PhD, professor of Statistical Science at Southern Methodist University in Dallas, Texas. 

In this "Breathe Easy Critical Perspective" podcast, Dr. Dominique Pepper interviews Dr. Michael Sjoding. They discuss his NEJM publication about bias in pulse oximetry measurement. Dr. Sjoding is an Assistant Professor in the Division of Pulmonary and Critical Care at the Uni ...

One of the hottest topics in modern physics is trying to understand the scattering of fundamental particles with neither shape nor size - one step up from nothingness. Amazingly, attempts to understand these simple processes theoretically require state-of-the-art mathematics. The ...  Show more

Tomas Kalincik, Head of the Clinical Outcomes Research Unit at the University of Melbourne, and Maria Pia Sormani, Professor of Biostatistics at the University of Genoa, discuss the use of real-world data to compare disease-modifying treatments (DMTs) in multiple sclerosis, inclu ...  Show more