Cardiac Consult: A Cleveland Clinic Podcast for Healthcare Professionals

Cardiac Consult: A Cleveland Clinic Podcast f...

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Evolving Strategies in Aortic Arch Repair

Eric Roselli, MD, and Patrick Vargo, MD, discuss how advances in open, hybrid and endovascular techniques are changing the treatment of aortic arch disease. They explore evolving approaches to aneurysms and dissections, innovations in brain protection and the role of specialized ...  Show more

Management of Complex Aortic Valve Endocarditis

Milind Desai, MD, and Per Wierup, MD, discuss the evaluation and management of high-risk aortic valve endocarditis, including indications for urgent intervention and timing of surgery. They also review operative approaches to patients with heart failure, uncontrolled infection an ...  Show more

Lepodisiran and the Emerging Role of Oxidized Phospholipids in Lipoprotein(a) Risk

Luke Laffin, MD, speaks with Steven Nissen, MD, about findings from the ALPACA trial evaluating lepodisiran and its effects on oxidized phospholipids and lipoprotein(a). They discuss the potential mechanisms linking lipoprotein(a) to cardiovascular risk and how ongoing phase 3 re ...  Show more

Talking Tall Rounds®: Updates on Less Invasive Cardiac Surgery

In this excerpt from Tall Rounds®, Gianluca Torregrossa, MD, discusses minimally invasive and totally endoscopic coronary artery bypass grafting (TECAB), highlighting procedural advances that enable multi-vessel revascularization through less invasive approaches. Looking to refer ...  Show more

CTX310 and the Future of Gene Editing for Lipid Disorders

Steven Nissen, MD, and Luke Laffin, MD, discuss one-year follow-up data for CTX310, a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3 to treat lipid disorders. They review the sustained reductions in LDL cholesterol and triglycerides, and the potential role of one-time gene-ed ...  Show more