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Dina Kao on a trial of lyophilised sterile faecal filtrate versus lyophilised conventional donor stool for recurrent Clostridiodes difficile infection

Can bacteria-free, sterile faecal filtrate match conventional faecal microbiota transplantation for recurrent C difficile infection? Dina Kao (University of Alberta) unpacks a landmark multicentre trial that tested this hypothesis, and we discuss what it tells us about the role o ...  Afficher plus

Premysl Bercik on a double-blind crossover trial of gluten and wheat in IBS

Do wheat or gluten trigger IBS symptoms? 

We spoke to Premysl Bercik about a randomised, double-blind, sham-controlled crossover trial that challenged adults with IBS—who reported benefit from a gluten-free diet—with wheat, gluten, or a gluten-free sham to test symptom a ...

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Julia Mayerle on the validation of plasma multimetabolite signatures for patients at risk of or with suspected pancreatic ductal adenocarcinoma

Can a multi-metabolite blood test improve early pancreatic cancer detection? We spoke to Julia Mayerle about the METAPAC study, which sought to validate the ability of plasma metabolic signatures to find resectable tumors and reduce unnecessary invasive procedures in high-risk ...

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Salvatore Piano on the global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis

How does acute kidney injury presentation and management differ globally for patients hospitalised with cirrhosis? 

We spoke to Salvatore Piano, corresponding author of the landmark International Club of Ascites GLOBAL AKI study, about new data on regional variations in ...

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John Chia on the ASCOLT trial of adjuvant aspirin for colorectal cancer

John Chia discusses the results of the ASCOLT trial, which explored the effect of aspirin after completion of standard adjuvant therapy for patients with colorectal cancer.

Read the full article:

<a href='https://www.thelancet.com/journals/langas/article/PIIS2468-1 ...

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