Episode #338: Who Loses Weight And Why

Stop a GLP-1 and about two thirds of the weight loss comes back within a year. Three randomized withdrawal trials (SURMOUNT-4, STEP 1 extension, STEP 4) and a new BMJ 2026 systematic review of 37 RCTs and nearly 10,000 adults all land on the same signal. The cardiometabolic benef ...  Afficher plus

Every week there's a new headline saying men are losing testosterone. A quarter of men now start testosterone replacement therapy without ever getting their blood tested. The supplement aisle is full of boosters that either do nothing or contain undisclosed steroids. And the lab ...  Afficher plus

If you've been curious about GLP-1s but assumed they're only for people with diabetes or major weight to lose—this episode will absolutely shift your perspective. Chalene sits down with Dr. Kathleen Jordan of MIDI Health to unpack everything from microdosing GLP-1s (like Ozempic ...  Afficher plus

Can weight loss meds help or hurt your health?" 🚨 Chalene Johnson and Sal Di Stefano uncover the truth about GLP-1s—are they the ultimate game-changer or a risky shortcut? This episode covers the science, myths, and practical strategies for using GLP-1 medications safely while m ...  Afficher plus

What if the solution to your health plateau isn’t adding more biohacks, but identifying the single hidden stressor that’s crushing everything else? Live from the Health Summit stage, Dr. Andy Galpin introduces the concepts of “performance anchors” and the “three I’s framework,” t ...  Afficher plus

Today, I am blessed to have Mike Mutzel here with me. Mike has a B.S. in Biology from Western Washington University and an M.S. in Clinical Nutrition from the University of Bridgeport and is a graduate of the Institute for Functional Medicine’s (IFM) Applying Functional Medicine ...  Afficher plus